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FLEXIBLE PARAMETRIC SURVIVAL ANALYSIS USING STATA: BEYOND THE COX MODEL

by Patrick Royston; Paul C. Lambert

Published by Stata Press. 1st. 2011

Very good condition. This book takes standard survival models into a wider realm, greatly increasing their usefulness. The starting point of the text is a basic understanding of survival analysis and how it is done in Stata. The aim of the text is for researchers to build on the illustrations and examples to apply the methodology to their own investigations of survival data. Cardwraps. xxvi and 347 pages including index.

Covers a little rubbed at edges. Text block slightly marked. Name in ink to top of half-title page. Contents clean.

ISBN: 9781597180795
Stock no. 1830305

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Contents

  • List of Tables
  • List of Figures
  • Preface
  • 1 Introduction
  • 1.1 Goals
  • 1.2 A brief review of the Cox proportional hazards model
  • 1.3 Beyond the Cox Model
  • 1.4 Why parametric models?
  • 1.5 Why not standard parametric models?
  • 1.6 A brief introduction to stpm2
  • 1.7 Basic relationships in survival analysis
  • 1.8 Comparing models
  • 1.9 The delta method
  • 1.10 Ado-file resources
  • 1.11 How our book is organised
  • 2 Using stset and stsplit
  • 2.1 What is the stset command?
  • 2.2 Some key concepts
  • 2.3 Syntax of the stset command
  • 2.4 Variables created by the stset command
  • 2.5 Examples of using stset
  • 2.6 The stsplit command
  • 1.7 Conclusion
  • 3 Graphical introduction to the principal datasets
  • 3.1 Introduction
  • 3.2 Rotterdam breast cancer data
  • 3.3 England and Wales breast cancel data
  • 3.4 Orchiectomy data
  • 3.5 Conclusion
  • 4. Poisson models
  • 4.1 Introduction
  • 4.2 Modelling rates with the Poisson distribution
  • 4.3 Splitting the time scale
  • 4.4 Collapsing the data to speed up computation
  • 4.5 Spitting at unique failure times
  • 4.6 Comparing a different number of intervals
  • 4.7 Fine splitting of the time scale
  • 4.8 Splines: Motivation and definition
  • 4.9 FP's: Motivation and definition
  • 4.10 Discussion
  • 5 Royston-Parmar models
  • 5.1 Motivation and introduction
  • 5.2 Proportional hazards models
  • 5.3 Selecting a spline function
  • 5.4 PO Models
  • 5.5 Pribit models
  • 5.6 Royston=Parmar (RP) models
  • 5.7 Concluding remarks
  • 6 Prognostic models
  • 6.1 Introduction
  • 6.2 Developing and reporting a prognostic model
  • 6.3 What does the baseline
  • 6.4 Model selection
  • 6.5 Quantitative outputs from the model
  • 6.6 Goodness of fit
  • 6.7 Discrimination and explained variation
  • 6.8 Out-of-Sample prediction: Concept and applications
  • 6.9 Visualization of survival times
  • 6.10 Discussion
  • 7 Time-dependent effects
  • 7.1 Introduction
  • 7.2 Definitions
  • 7.3 What do we mean by a TD effect?
  • 7.4 Proportional on which scale?
  • 7.5 Poisson models with TD effects
  • 7.6 RP models with TD effects
  • 7.7 TD effects for continuous variables
  • 7.8 Attained age as the time scale
  • 7.9 Multiple time scales
  • 7.10 Prognostic models with TD effects
  • 7.11 Discussion
  • 8 Relative survival
  • 8.1 Introduction
  • 8.2 What is relative survival
  • 8.3 Excess mortality and relative survival
  • 8.4 Motivating example
  • 8.5 Life-table estimation of relative survival
  • 8.6 Poisson models for relative survival
  • 8.7 RP models with relative survival
  • 8.8 Some comments on model selection
  • 8.9 Age as a continuous variable
  • 8.10 Concluding remarks
  • 9 Further topics
  • 9.1 Introduction
  • 9.2 Number needed to treat
  • 9.3 Average and adjusted survival curves
  • 9.4 Modelling distributions with RP models
  • 9.5 Multiple events
  • 9.6 Bayesian RP Models
  • 9.7 Competing risks
  • 9.8 Period analysis
  • 9.9 Crude probability of death from relative survival models
  • 9.10 Final remarks
  • References
  • Author Index
  • Subject Index

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